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Transforming the Treatment and Prevention of Leprosy and Buruli Ulcers in Low and Middle Income Countries

Three Study Centres: India, Nepal, Nigeria.

Work Package 1 – Improving Quality of Care in Community (leprosy) 

Objective 1: Developing guidelines for leprosy centres and health centres to promote and support self-care with particular emphasis on prevention of recurrence of ulcers in the community.

Objective 2: Adapting the above self-care guidelines and implementing them locally.

  1. Nepal: Self-Help Evaluation for Leprosy and other conditions in Nepal (SHERPA)
  2. SE Nigeria: Implementation Science STudy In Leprosy (INSTIL Nigeria)
  3. NC Nigeria: SusTainability (Abuja) Retrospective Study (STARS): An investigation into the sustainability of community-based self-help and self-care interventions in the context of leprosy and the work of leprosy missions
  4. India: Sustainability of self-help groups in Chattisgarh State, India

Work Package 2 – Health Needs Assessment for Buruli Ulcers 

Objective: Undertake a health needs assessment of people admitted to hospital with BU in order to understand their needs for healthcare and the barriers to further access they may encounter.

This WP has two studies:

  1. Health Assessment Needs in Buruli Ulcer (HABU) prospective.
  2. Health Assessment Needs in Buruli Ulcer (HABU) retrospective

Work Package 3 – Clinical Research (Efficacy Trial) 

Objective: Implementing one efficacy trial of a promising and inexpensive regenerative medicine intervention (Trial of Autologous Blood products to promote ulcer healing in LEprosy, TABLE) study

Strategic Priorities